Version 5.4
Mus musculus Gene: Hsd17b14
Summary
InnateDB Gene IDBG-183702.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hsd17b14
Gene Name hydroxysteroid (17-beta) dehydrogenase 14
Synonyms 0610039E24Rik; Dhrs10; retSDR3
Species Mus musculus
Ensembl Gene ENSMUSG00000030825
Encoded Proteins
IDBP-266004
hydroxysteroid (17-beta) dehydrogenase 14
IDBP-541634
hydroxysteroid (17-beta) dehydrogenase 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000087076:
17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:45554893-45567752
Strand Forward strand
Band B3
Transcripts
ENSMUST00000115479
ENSMUST00000107752 ENSMUSP00000103381
ENSMUST00000133242 ENSMUSP00000121017
ENSMUST00000141247
ENSMUST00000147958
ENSMUST00000150887
ENSMUST00000175711
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0004303 estradiol 17-beta-dehydrogenase activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity
GO:0050662 coenzyme binding
Biological Process
GO:0006694 steroid biosynthetic process
GO:0006706 steroid catabolic process
GO:0008152 metabolic process
GO:0044237 cellular metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005813 centrosome
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000087076
View Gene Order
ENSBTAG00000009174
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.285710
RefSeq NM_025330
OMIM
CCDS CCDS21251
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca