Version 5.4
Bos taurus Gene: HSD17B14
Summary
InnateDB Gene IDBG-640296.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSD17B14
Gene Name 17-beta-hydroxysteroid dehydrogenase 14
Synonyms retSDR3; SDR3
Species Bos taurus
Ensembl Gene ENSBTAG00000009174
Encoded Proteins
IDBP-692544
17-beta-hydroxysteroid dehydrogenase 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000087076:
17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:55878571-55899034
Strand Reverse strand
Band
Transcripts
ENSBTAT00000012090 ENSBTAP00000012090
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004303 estradiol 17-beta-dehydrogenase activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity
GO:0050662 coenzyme binding
Biological Process
GO:0006629 lipid metabolic process
GO:0006706 steroid catabolic process
GO:0008152 metabolic process
GO:0008202 steroid metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000087076
View Gene Order
ENSMUSG00000030825
View Gene Order
Cross-References
SwissProt Q9MYP6
TrEMBL
UniProt Splice Variant
Entrez Gene 282652
UniGene Bt.88264
RefSeq NM_174701
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF202997 AF238859
GenPept AAF44666 AAF62401
RNA Seq Atlas 282652

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca