InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Bcat2

Summary

InnateDB Gene

IDBG-183740.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bcat2

Gene Name

branched chain aminotransferase 2, mitochondrial

Synonyms

Bcat-2; Eca40

Species

Mus musculus

Ensembl Gene

ENSMUSG00000030826

Encoded Proteins

IDBP-183742

branched chain aminotransferase 2, mitochondrial

IDBP-400798

branched chain aminotransferase 2, mitochondrial

IDBP-400796

branched chain aminotransferase 2, mitochondrial

IDBP-400797

branched chain aminotransferase 2, mitochondrial

IDBP-534329

branched chain aminotransferase 2, mitochondrial

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105552:
This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:45570153-45589710

Strand

Forward strand

Band

Transcripts

ENSMUST00000033098	ENSMUSP00000033098
ENSMUST00000120864	ENSMUSP00000113045
ENSMUST00000120296	ENSMUSP00000112973
ENSMUST00000117366	ENSMUSP00000112933
ENSMUST00000153219
ENSMUST00000140077	ENSMUSP00000122023
ENSMUST00000148275

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004084	branched-chain-amino-acid transaminase activity
GO:0052654	L-leucine transaminase activity
GO:0052655	L-valine transaminase activity
GO:0052656	L-isoleucine transaminase activity

Biological Process

GO:0006549	isoleucine metabolic process
GO:0006550	isoleucine catabolic process
GO:0006551	leucine metabolic process
GO:0006573	valine metabolic process
GO:0008152	metabolic process
GO:0009081	branched-chain amino acid metabolic process
GO:0009082	branched-chain amino acid biosynthetic process
GO:0009083	branched-chain amino acid catabolic process
GO:0010817	regulation of hormone levels