InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bcat2

Summary

InnateDB Protein

IDBP-183742.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bcat2

Protein Name

branched chain aminotransferase 2, mitochondrial

Synonyms

Bcat-2; Eca40;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000033098

InnateDB Gene

IDBG-183740 (Bcat2)

Protein Structure

UniProt Annotation

Function

Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids.

Subcellular Localization

Mitochondrion.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004084	branched-chain-amino-acid transaminase activity
GO:0052654	L-leucine transaminase activity
GO:0052655	L-valine transaminase activity
GO:0052656	L-isoleucine transaminase activity

Biological Process

GO:0006549	isoleucine metabolic process
GO:0006550	isoleucine catabolic process
GO:0006551	leucine metabolic process
GO:0006573	valine metabolic process
GO:0008152	metabolic process
GO:0009081	branched-chain amino acid metabolic process
GO:0009082	branched-chain amino acid biosynthetic process
GO:0009083	branched-chain amino acid catabolic process
GO:0010817	regulation of hormone levels