Mus musculus Gene: Kcnq4 | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Gene | IDBG-183829.6 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | Kcnq4 | ||||||||||||||
Gene Name | potassium voltage-gated channel, subfamily Q, member 4 | ||||||||||||||
Synonyms | |||||||||||||||
Species | Mus musculus | ||||||||||||||
Ensembl Gene | ENSMUSG00000028631 | ||||||||||||||
Encoded Proteins |
potassium voltage-gated channel, subfamily Q, member 4
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Protein Structure | |||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
Entrez Gene | |||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117013:
The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||
Type | Protein coding | ||||||||||||||
Genomic Location | Chromosome 4:120696138-120748612 | ||||||||||||||
Strand | Reverse strand | ||||||||||||||
Band | D2.2 | ||||||||||||||
Transcripts |
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Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME |
Potassium Channels pathway
Neuronal System pathway
Voltage gated Potassium channels pathway
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KEGG | |||||||||||||||
INOH | |||||||||||||||
PID NCI | |||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME |
Voltage gated Potassium channels pathway
Neuronal System pathway
Potassium Channels pathway
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KEGG | |||||||||||||||
INOH | |||||||||||||||
PID NCI | |||||||||||||||
Cross-References | |||||||||||||||
SwissProt | |||||||||||||||
TrEMBL | |||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | |||||||||||||||
UniGene | Mm.397739 | ||||||||||||||
RefSeq | NM_001081142 | ||||||||||||||
OMIM | |||||||||||||||
CCDS | CCDS38865 | ||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
MGI ID | |||||||||||||||
MGI Symbol | |||||||||||||||
EMBL | |||||||||||||||
GenPept | |||||||||||||||
RNA Seq Atlas | |||||||||||||||