Version 5.4
Mus musculus Gene: Txlng
Summary
InnateDB Gene IDBG-183843.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Txlng
Gene Name taxilin gamma
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038344
Encoded Proteins
IDBP-183845
taxilin gamma
IDBP-256263
taxilin gamma
IDBP-256265
taxilin gamma
IDBP-256267
taxilin gamma
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000086712:
This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:162778919-162829454
Strand Reverse strand
Band F4
Transcripts
ENSMUST00000041370 ENSMUSP00000038615
ENSMUST00000112316 ENSMUSP00000107935
ENSMUST00000112315 ENSMUSP00000107934
ENSMUST00000112314 ENSMUSP00000107933
ENSMUST00000131463
ENSMUST00000150080
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019905 syntaxin binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007049 cell cycle
GO:0010564 regulation of cell cycle process
GO:0030500 regulation of bone mineralization
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005829 cytosol
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000086712
View Gene Order
ENSBTAG00000001768
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
fra_pathway
Validated transcriptional targets of AP1 family members Fra1 and Fra2
Cross-References
SwissProt Q8BHN1
TrEMBL A2AFJ4 Q3TT61
UniProt Splice Variant
Entrez Gene 353170
UniGene Mm.371732 Mm.411684 Mm.421922 Mm.421928 Mm.490654
RefSeq NM_001290776 NM_001290777 NM_178935 XM_006528891
OMIM
CCDS CCDS30510 CCDS72463
HPRD
IMGT
MGI ID MGI:3590652
MGI Symbol Txlng
EMBL AK030100 AK031783 AK044130 AK078477 AK161561 AL672123 BC117898 BC117899 DQ316984 DQ320011
GenPept AAI17899 AAI17900 ABC47035 ABC60327 BAC26785 BAC27547 BAC31791 BAC37296 BAE36464 CAM24319 CAM24320
RNA Seq Atlas 353170

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca