InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Txlng

Summary

InnateDB Protein

IDBP-256265.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Txlng

Protein Name

taxilin gamma

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000107934

InnateDB Gene

IDBG-183843 (Txlng)

Protein Structure

UniProt Annotation

Function

May be involved in intracellular vesicle traffic (By similarity). Inhibits ATF4-mediated transcription, possibly by dimerizing with ATF4 to form inactive dimers that cannot bind DNA. May be involved in regulating bone mass density through an ATF4- dependent pathway. May be involved in cell cycle progression. {ECO:0000250, ECO:0000269PubMed:15911876, ECO:0000269PubMed:19016261, ECO:0000269PubMed:19913514}.

Subcellular Localization

Nucleus membrane. Cytoplasm, cytosol.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019905	syntaxin binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007049	cell cycle
GO:0030500	regulation of bone mineralization
GO:0051726	regulation of cell cycle