Version 5.4
Mus musculus Gene: Dtymk
Summary
InnateDB Gene IDBG-183866.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dtymk
Gene Name deoxythymidylate kinase
Synonyms AU044245; CDC8; D10Ertd203e; mtmk; Tmk; TMPK; TYPK
Species Mus musculus
Ensembl Gene ENSMUSG00000026281
Encoded Proteins
IDBP-183868
deoxythymidylate kinase
IDBP-255032
deoxythymidylate kinase
IDBP-255034
deoxythymidylate kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168393:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:93792576-93801934
Strand Reverse strand
Band D
Transcripts
ENSMUST00000027503 ENSMUSP00000027503
ENSMUST00000112893 ENSMUSP00000108514
ENSMUST00000112890 ENSMUSP00000108511
ENSMUST00000144106
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004798 thymidylate kinase activity
GO:0005524 ATP binding
GO:0050145 nucleoside phosphate kinase activity
Biological Process
GO:0006233 dTDP biosynthetic process
GO:0006235 dTTP biosynthetic process
GO:0009165 nucleotide biosynthetic process
GO:0043627 response to estrogen
GO:0045445 myoblast differentiation
GO:0046686 response to cadmium ion
GO:0046939 nucleotide phosphorylation
GO:0046940 nucleoside monophosphate phosphorylation
GO:0071363 cellular response to growth factor stimulus
Cellular Component
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0005759 mitochondrial matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000168393
View Gene Order
ENSBTAG00000015408
Not yet available
Pathways
NETPATH
REACTOME
REACT_238368
Synthesis and interconversion of nucleotide di- and triphosphates pathway
REACT_188937
Metabolism pathway
REACT_245662
Metabolism of nucleotides pathway
KEGG
mmu00240
Pyrimidine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_21330
Synthesis and interconversion of nucleotide di- and triphosphates pathway
REACT_1698
Metabolism of nucleotides pathway
REACT_111217
Metabolism pathway
KEGG
hsa00240
Pyrimidine metabolism pathway
INOH
INOH website
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.250332
RefSeq NM_001105667 NM_023136
OMIM
CCDS CCDS35672 CCDS48329
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca