Version 5.4
Mus musculus Gene: Ttc19
Summary
InnateDB Gene IDBG-184090.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ttc19
Gene Name tetratricopeptide repeat domain 19
Synonyms 2010204O13Rik; 2810460C24Rik; AI505442
Species Mus musculus
Ensembl Gene ENSMUSG00000042298
Encoded Proteins
IDBP-184092
tetratricopeptide repeat domain 19
IDBP-184096
tetratricopeptide repeat domain 19
IDBP-540330
tetratricopeptide repeat domain 19
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000011295:
This gene encodes a protein with a tetratricopeptide repeat (TPR) domain containing several TPRs of about 34 aa each. These repeats are found in a variety of organisms including bacteria, fungi and plants, and are involved in a variety of functions including protein-protein interactions. This protein is embedded in the inner mitochondrial membrane and is involved in the formation of the mitochondrial respiratory chain III. It has also been suggested that this protein plays a role in cytokinesis. Mutations in this gene cause mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:62281473-62328451
Strand Forward strand
Band B2
Transcripts
ENSMUST00000101075 ENSMUSP00000098636
ENSMUST00000050646 ENSMUSP00000054367
ENSMUST00000136477
ENSMUST00000162385 ENSMUSP00000125618
ENSMUST00000154976
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0034551 mitochondrial respiratory chain complex III assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000011295
View Gene Order
ENSBTAG00000013270
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.397996 Mm.400797 Mm.489722 Mm.69739
RefSeq NM_028360 NM_029704
OMIM
CCDS CCDS36177 CCDS48817
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca