Version 5.4
Mus musculus Gene: Mep1a
Summary
InnateDB Gene IDBG-184220.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mep1a
Gene Name meprin 1 alpha
Synonyms AI098089; AW107200; Mep-1; Mep-1a; Mep1
Species Mus musculus
Ensembl Gene ENSMUSG00000023914
Encoded Proteins
IDBP-184222
meprin 1 alpha
IDBP-400857
meprin 1 alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112818:
Gene Information
Type Protein coding
Genomic Location Chromosome 17:43474324-43502812
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000024707 ENSMUSP00000024707
ENSMUST00000117137 ENSMUSP00000113838
ENSMUST00000130964
ENSMUST00000152155
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane
GO:0017090 meprin A complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000112818
View Gene Order
ENSBTAG00000004345
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04974
Protein digestion and absorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04974
Protein digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt P28825
TrEMBL Q3TP44 Q3UWD0
UniProt Splice Variant
Entrez Gene 17287
UniGene Mm.5346
RefSeq NM_008585 XM_006523751
OMIM
CCDS CCDS37623
HPRD
IMGT
MGI ID MGI:96963
MGI Symbol Mep1a
EMBL AK136455 AK164734 BC015258 CT010585 M74897 U62765
GenPept AAA75354 AAC53194 AAH15258 BAE22985 BAE37893 CAQ11110
RNA Seq Atlas 17287

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca