Version 5.4
Mus musculus Gene: Sult2b1
Summary
InnateDB Gene IDBG-184312.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sult2b1
Gene Name sulfotransferase family, cytosolic, 2B, member 1
Synonyms AI326997; BB173635; ST2B1; SULT2B
Species Mus musculus
Ensembl Gene ENSMUSG00000003271
Encoded Proteins
IDBP-184314
sulfotransferase family, cytosolic, 2B, member 1
IDBP-266047
sulfotransferase family, cytosolic, 2B, member 1
IDBP-541396
sulfotransferase family, cytosolic, 2B, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000088002:
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:45729983-45759612
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000075571 ENSMUSP00000075005
ENSMUST00000107735 ENSMUSP00000103363
ENSMUST00000140127 ENSMUSP00000121262
ENSMUST00000123250
ENSMUST00000138525
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004027 alcohol sulfotransferase activity
GO:0005515 protein binding
GO:0008146 sulfotransferase activity
GO:0050294 steroid sulfotransferase activity
Biological Process
GO:0000103 sulfate assimilation
GO:0008202 steroid metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000088002
View Gene Order
ENSBTAG00000045498
Not yet available
Pathways
NETPATH
REACTOME
REACT_241116
Cytosolic sulfonation of small molecules pathway
REACT_243247
Phase II conjugation pathway
REACT_188937
Metabolism pathway
REACT_232343
Biological oxidations pathway
KEGG
mmu00140
Steroid hormone biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00140
Steroid hormone biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.271634
RefSeq NM_017465 XM_006540997 XM_006541000
OMIM
CCDS CCDS21263
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca