Version 5.4
Mus musculus Gene: Slc6a12
Summary
InnateDB Gene IDBG-184525.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc6a12
Gene Name solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
Synonyms BGT1; Gabt2; GAT2
Species Mus musculus
Ensembl Gene ENSMUSG00000030109
Encoded Proteins
IDBP-184527
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
IDBP-623254
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
IDBP-623256
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
IDBP-623262
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
IDBP-623264
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
IDBP-623268
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
IDBP-623270
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111181:
Gene Information
Type Protein coding
Genomic Location Chromosome 6:121343076-121365775
Strand Forward strand
Band F1
Transcripts
ENSMUST00000032200 ENSMUSP00000032200
ENSMUST00000166457 ENSMUSP00000126937
ENSMUST00000168295 ENSMUSP00000129389
ENSMUST00000166390 ENSMUSP00000128217
ENSMUST00000171008 ENSMUSP00000126708
ENSMUST00000171874
ENSMUST00000170582
ENSMUST00000165456 ENSMUSP00000130715
ENSMUST00000163771 ENSMUSP00000127779
ENSMUST00000170339
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005328 neurotransmitter:sodium symporter activity
GO:0005332 gamma-aminobutyric acid:sodium symporter activity
Biological Process
GO:0006836 neurotransmitter transport
GO:0009992 cellular water homeostasis
GO:0010033 response to organic substance
GO:0015812 gamma-aminobutyric acid transport
GO:0055085 transmembrane transport
GO:0071474 cellular hyperosmotic response
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000111181
View Gene Order
ENSBTAG00000038415
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20506
Na+/Cl- dependent neurotransmitter transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_13796
Amino acid transport across the plasma membrane pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_813
Creatine metabolism pathway
REACT_23910
Reuptake of GABA pathway
REACT_23947
GABA synthesis, release, reuptake and degradation pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_13685
Neuronal System pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_13477
Transmission across Chemical Synapses pathway
REACT_13723
Neurotransmitter Release Cycle pathway
REACT_111217
Metabolism pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.274506
RefSeq NM_133661 XM_006505533 XM_006505534 XM_006505535 XM_006505536
OMIM
CCDS CCDS39616
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca