Mus musculus Gene: Pign
Summary
InnateDB Gene IDBG-185188.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pign
Gene Name phosphatidylinositol glycan anchor biosynthesis, class N
Synonyms Gm20308; PIG-N
Species Mus musculus
Ensembl Gene ENSMUSG00000056536
Encoded Proteins
phosphatidylinositol glycan anchor biosynthesis, class N
phosphatidylinositol glycan anchor biosynthesis, class N
phosphatidylinositol glycan anchor biosynthesis, class N
phosphatidylinositol glycan anchor biosynthesis, class N
phosphatidylinositol glycan anchor biosynthesis, class N
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197563:
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is expressed in the endoplasmic reticulum and transfers phosphoethanolamine (EtNP) to the first mannose of the GPI anchor. Two alternatively spliced variants, which encode an identical isoform, have been reported. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:105518422-105663677
Strand Reverse strand
Band E2.1
Transcripts
ENSMUST00000070699 ENSMUSP00000069969
ENSMUST00000186485 ENSMUSP00000139638
ENSMUST00000190945
ENSMUST00000190139
ENSMUST00000187537 ENSMUSP00000140020
ENSMUST00000190811 ENSMUSP00000140844
ENSMUST00000186195 ENSMUSP00000139490
ENSMUST00000185983
ENSMUST00000191408
ENSMUST00000188858
ENSMUST00000187909
ENSMUST00000185209
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0008484 sulfuric ester hydrolase activity
GO:0016740 transferase activity
GO:0016780 phosphotransferase activity, for other substituted phosphate groups
Biological Process
GO:0006506 GPI anchor biosynthetic process
GO:0008152 metabolic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Synthesis of glycosylphosphatidylinositol (GPI) pathway
Post-translational modification: synthesis of GPI-anchored proteins pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL G3X9F1
UniProt Splice Variant
Entrez Gene 27392
UniGene
RefSeq NM_013784 XM_006529678 XM_006529675 XM_006529676
OMIM
CCDS CCDS15205
HPRD
IMGT
MGI ID MGI:1351629
MGI Symbol Pign
EMBL AC132082 AC166354 CH466520
GenPept EDL39874
RNA Seq Atlas 27392