Version 5.4
Mus musculus Gene: Slc25a3
Summary
InnateDB Gene IDBG-185245.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc25a3
Gene Name solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
Synonyms 5730556H19Rik; Phc; PTP
Species Mus musculus
Ensembl Gene ENSMUSG00000061904
Encoded Proteins
IDBP-185247
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
IDBP-625500
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
IDBP-625501
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
IDBP-625504
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000075415:
The protein encoded by this gene catalyzes the transport of phosphate into the mitochondrial matrix, either by proton cotransport or in exchange for hydroxyl ions. The protein contains three related segments arranged in tandem which are related to those found in other characterized members of the mitochondrial carrier family. Both the N-terminal and C-terminal regions of this protein protrude toward the cytosol. Multiple alternatively spliced transcript variants have been isolated. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:91116574-91124059
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000076694 ENSMUSP00000075987
ENSMUST00000163246 ENSMUSP00000129301
ENSMUST00000170810 ENSMUSP00000127098
ENSMUST00000164505 ENSMUSP00000132480
ENSMUST00000167455
ENSMUST00000169339
ENSMUST00000171960
ENSMUST00000172442
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 64 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 64 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015293 symporter activity
GO:0032403 protein complex binding
Biological Process
GO:0006810 transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000075415
View Gene Order
ENSBTAG00000012890
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
cmyb_pathway
C-MYB transcription factor network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.298 Mm.398829 Mm.475470
RefSeq NM_133668 XM_006513371 XM_006544326 XM_006544327
OMIM
CCDS CCDS24121
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca