Version 5.4
| Mus musculus Gene: Klrg1 | |||||
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| Summary | |||||
| InnateDB Gene | IDBG-185261.6 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | Klrg1 | ||||
| Gene Name | killer cell lectin-like receptor subfamily G, member 1 | ||||
| Synonyms | 2F1-Ag; MAFA; MAFA-L | ||||
| Species | Mus musculus | ||||
| Ensembl Gene | ENSMUSG00000030114 | ||||
| Encoded Proteins |
killer cell lectin-like receptor subfamily G, member 1
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| Protein Structure | |||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||
| Entrez Gene | |||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139187:
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. Alternatively spliced transcript variants have been reported, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||
| Type | Protein coding | ||||
| Genomic Location | Chromosome 6:122270596-122282882 | ||||
| Strand | Reverse strand | ||||
| Band | F1 | ||||
| Transcripts |
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| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||
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Species
Homo sapiens
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Gene ID
Gene Order
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| Pathways | |||||
| NETPATH | |||||
| REACTOME |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Immune System pathway
Adaptive Immune System pathway
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| KEGG | |||||
| INOH | |||||
| PID NCI | |||||
| Pathway Predictions based on Human Orthology Data | |||||
| NETPATH | |||||
| REACTOME |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Adaptive Immune System pathway
Immune System pathway
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| KEGG | |||||
| INOH | |||||
| PID NCI | |||||
| Cross-References | |||||
| SwissProt | |||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | |||||
| UniGene | Mm.20434 | ||||
| RefSeq | NM_016970 | ||||
| OMIM | |||||
| CCDS | CCDS20492 | ||||
| HPRD | |||||
| IMGT | |||||
| MGI ID | |||||
| MGI Symbol | |||||
| EMBL | |||||
| GenPept | |||||
| RNA Seq Atlas | |||||