Version 5.4
Mus musculus Gene: Tmpo
Summary
InnateDB Gene IDBG-185294.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmpo
Gene Name thymopoietin
Synonyms 5630400D24Rik; AI195756; AI606875; AW214352; AW547477; LAP2; TP
Species Mus musculus
Ensembl Gene ENSMUSG00000019961
Encoded Proteins
IDBP-185296
thymopoietin
IDBP-185300
thymopoietin
IDBP-185302
thymopoietin
IDBP-185304
thymopoietin
IDBP-271188
thymopoietin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120802:
The protein encoded by this gene resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in this gene are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:91147571-91171582
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000072239 ENSMUSP00000072092
ENSMUST00000092219 ENSMUSP00000089864
ENSMUST00000099355 ENSMUSP00000096956
ENSMUST00000020123 ENSMUSP00000020123
ENSMUST00000105293 ENSMUSP00000100930
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 42 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005637 nuclear inner membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000120802
View Gene Order
ENSBTAG00000004240
Not yet available
Cross-References
SwissProt Q61029
TrEMBL Q3TXQ1
UniProt Splice Variant
Entrez Gene 21917
UniGene Mm.397329 Mm.409968
RefSeq NM_001080132 NM_001080129 NM_001080130 NM_001080131 NM_001283048 NM_011605
OMIM
CCDS CCDS36032 CCDS24122 CCDS36033 CCDS36034 CCDS36035
HPRD
IMGT
MGI ID MGI:106920
MGI Symbol Tmpo
EMBL AK150305 AK150515 AK153281 AK159161 AK165851 CH466539 U39074 U39075 U39076 U39077
GenPept AAC52574 AAC52575 AAC52576 AAC52577 BAE29455 BAE29627 BAE31865 BAE34864 BAE38413 EDL21533
RNA Seq Atlas 21917

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca