Version 5.4
Mus musculus Gene: Tmod2
Summary
InnateDB Gene IDBG-185313.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmod2
Gene Name tropomodulin 2
Synonyms N-Tmod; NTMOD
Species Mus musculus
Ensembl Gene ENSMUSG00000032186
Encoded Proteins
IDBP-185315
tropomodulin 2
IDBP-185317
tropomodulin 2
IDBP-624423
tropomodulin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000128872:
This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:75565621-75611325
Strand Reverse strand
Band D
Transcripts
ENSMUST00000064433 ENSMUSP00000069956
ENSMUST00000098552 ENSMUSP00000096152
ENSMUST00000164100 ENSMUSP00000126739
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005523 tropomyosin binding
Biological Process
GO:0007270 neuron-neuron synaptic transmission
GO:0007611 learning or memory
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0030426 growth cone
GO:0043005 neuron projection
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000128872
View Gene Order
ENSBTAG00000014011
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.291880 Mm.403876 Mm.471918 Mm.472133 Mm.488065
RefSeq NM_001038710 NM_016711 XM_006511267 XM_006511268
OMIM
CCDS CCDS23345
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca