Version 5.4
Mus musculus Gene: Cdh16
Summary
InnateDB Gene IDBG-185772.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdh16
Gene Name cadherin 16
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000031881
Encoded Proteins
IDBP-621785
cadherin 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166589:
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:104614141-104624396
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000163783 ENSMUSP00000129663
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
GO:0016339 calcium-dependent cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166589
View Gene Order
ENSBTAG00000009585
Not yet available
Cross-References
SwissProt O88338
TrEMBL Q546A8
UniProt Splice Variant
Entrez Gene 12556
UniGene Mm.19423
RefSeq NM_001252627 NM_001252628 NM_007663
OMIM
CCDS CCDS22583
HPRD
IMGT
MGI ID MGI:106671
MGI Symbol Cdh16
EMBL AF016271 AF118228 AJ609635 BC015251 CH466525
GenPept AAC34254 AAF28836 AAH15251 CAE82011 EDL11223
RNA Seq Atlas 12556

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca