Version 5.4
Mus musculus Gene: Mad2l1bp
Summary
InnateDB Gene IDBG-186056.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mad2l1bp
Gene Name MAD2L1 binding protein
Synonyms 0610009D16Rik; 2510031P20Rik; AU018945; AW550977; C76045; CMT2A; CMT2B; Mad2lbp; mKIAA0110
Species Mus musculus
Ensembl Gene ENSMUSG00000034509
Encoded Proteins
IDBP-623822
MAD2L1 binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124688:
The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:46147390-46153553
Strand Reverse strand
Band C
Transcripts
ENSMUST00000171172 ENSMUSP00000125915
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007093 mitotic cell cycle checkpoint
GO:0007094 mitotic spindle assembly checkpoint
GO:0007096 regulation of exit from mitosis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124688
View Gene Order
ENSBTAG00000009548
Not yet available
Cross-References
SwissProt Q9DCX1
TrEMBL
UniProt Splice Variant
Entrez Gene 66591
UniGene Mm.272024
RefSeq NM_025649
OMIM
CCDS CCDS28821
HPRD
IMGT
MGI ID MGI:1913841
MGI Symbol Mad2l1bp
EMBL AK002377 AK004224 BC005768
GenPept AAH05768 BAB22054 BAB23226
RNA Seq Atlas 66591

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca