Version 5.4
Mus musculus Gene: Xpo5
Summary
InnateDB Gene IDBG-186220.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Xpo5
Gene Name exportin 5
Synonyms 2410004H11Rik; 2700038C24Rik; AI648907; AW549301; Exp5; mKIAA1291; RanBp21
Species Mus musculus
Ensembl Gene ENSMUSG00000067150
Encoded Proteins
IDBP-186222
exportin 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124571:
This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:46202855-46242299
Strand Forward strand
Band C
Transcripts
ENSMUST00000087031 ENSMUSP00000084257
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000049 tRNA binding
GO:0005488 binding
GO:0005515 protein binding
GO:0008536 Ran GTPase binding
GO:0008565 protein transporter activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006611 protein export from nucleus
GO:0006886 intracellular protein transport
GO:0031047 gene silencing by RNA
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124571
View Gene Order
ENSBTAG00000018970
Not yet available
Pathways
NETPATH
REACTOME
REACT_221178
MicroRNA (miRNA) biogenesis pathway
REACT_233572
Gene Expression pathway
REACT_206535
Regulatory RNA pathways pathway
KEGG
mmu03013
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_12417
MicroRNA (miRNA) biogenesis pathway
REACT_71
Gene Expression pathway
REACT_12472
Regulatory RNA pathways pathway
KEGG
hsa03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt Q924C1
TrEMBL
UniProt Splice Variant
Entrez Gene 72322
UniGene Mm.275039
RefSeq NM_028198
OMIM
CCDS CCDS37631
HPRD
IMGT
MGI ID MGI:1913789
MGI Symbol Xpo5
EMBL AF343581 AK010389 AK011190 AK122486 BC055455 BC131661
GenPept AAH55455 AAI31662 AAK68050 BAB26904 BAB27455 BAC65768
RNA Seq Atlas 72322

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca