Mus musculus Gene: Saa1
Summary
InnateDB Gene IDBG-186408.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Saa1
Gene Name serum amyloid A 1
Synonyms Saa-1; Saa2
Species Mus musculus
Ensembl Gene ENSMUSG00000074115
Encoded Proteins
serum amyloid A 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:46740501-46742980
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000128088 ENSMUSP00000119150
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008201 heparin binding
Biological Process
GO:0006953 acute-phase response
GO:0008203 cholesterol metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0034364 high-density lipoprotein particle
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
TRAF6 mediated NF-kB activation pathway
Toll Like Receptor 3 (TLR3) Cascade pathway
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation pathway
Toll Like Receptor 2 (TLR2) Cascade pathway
Innate Immune System pathway
GPCR downstream signaling pathway
Disease pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
MyD88 cascade initiated on plasma membrane pathway
Amyloids pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Toll Like Receptor TLR1:TLR2 Cascade pathway
ZBP1(DAI) mediated induction of type I IFNs pathway
Immune System pathway
Binding and Uptake of Ligands by Scavenger Receptors pathway
Toll Like Receptor 5 (TLR5) Cascade pathway
Toll Like Receptor TLR6:TLR2 Cascade pathway
Advanced glycosylation endproduct receptor signaling pathway
Toll Like Receptor 9 (TLR9) Cascade pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
DEx/H-box helicases activate type I IFN and inflammatory cytokines production pathway
Toll-Like Receptors Cascades pathway
MyD88 dependent cascade initiated on endosome pathway
Cytosolic sensors of pathogen-associated DNA pathway
G alpha (i) signalling events pathway
RIP-mediated NFkB activation via ZBP1 pathway
Activated TLR4 signalling pathway
G alpha (q) signalling events pathway
MyD88-independent cascade pathway
Signal Transduction pathway
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways pathway
Toll Like Receptor 7/8 (TLR7/8) Cascade pathway
MyD88:Mal cascade initiated on plasma membrane pathway
TRIF-mediated TLR3/TLR4 signaling pathway
TAK1 activates NFkB by phosphorylation and activation of IKKs complex pathway
Scavenging by Class B Receptors pathway
Formyl peptide receptors bind formyl peptides and many other ligands pathway
Toll Like Receptor 10 (TLR10) Cascade pathway
Toll Like Receptor 4 (TLR4) Cascade pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P05366
TrEMBL Q5I0U6
UniProt Splice Variant
Entrez Gene 20208
UniGene
RefSeq NM_009117 XM_006540724 XM_006540725 XM_006540726
OMIM
CCDS CCDS21284
HPRD
IMGT
MGI ID MGI:98221
MGI Symbol Saa1
EMBL BC087933 CH466603 M11131 M13521
GenPept AAA40083 AAA40084 AAH87933 EDL22938
RNA Seq Atlas 20208