Version 5.4
Mus musculus Protein: Saa1
Summary
InnateDB Protein IDBP-542520.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Saa1
Protein Name serum amyloid A 1
Synonyms Saa-1; Saa2;
Species Mus musculus
Ensembl Protein ENSMUSP00000119150
InnateDB Gene IDBG-186408 (Saa1)
Protein Structure
UniProt Annotation
Function Major acute phase protein. {ECO:0000269PubMed:9518179}.
Subcellular Localization Secreted {ECO:0000269PubMed:9518179}.
Disease Associations
Tissue Specificity Detected in blood plasma (at protein level). Detected in liver. {ECO:0000269PubMed:3857624, ECO:0000269PubMed:9518179}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008201 heparin binding
Biological Process
GO:0006953 acute-phase response
GO:0008203 cholesterol metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0034364 high-density lipoprotein particle
Protein Structure and Domains
PDB ID MGI:98221
InterPro IPR000096 Serum amyloid A protein
PFAM PF00277
PRINTS PR00306
PIRSF PIRSF002472
SMART SM00197
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P05366
PhosphoSite PhosphoSite-P05366
TrEMBL Q5I0U6
UniProt Splice Variant
Entrez Gene 20208
UniGene
RefSeq NP_033143
MGI ID
MGI Symbol Saa1
OMIM
CCDS CCDS21284
HPRD
IMGT
EMBL BC087933 CH466603 M11131 M13521
GenPept AAA40083 AAA40084 AAH87933 EDL22938

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca