Version 5.4
Mus musculus Gene: Tjap1
Summary
InnateDB Gene IDBG-186703.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tjap1
Gene Name tight junction associated protein 1
Synonyms 0610041D19Rik; AI415281; AW121008; Pilt; Tjp4
Species Mus musculus
Ensembl Gene ENSMUSG00000012296
Encoded Proteins
IDBP-186705
tight junction associated protein 1
IDBP-624054
tight junction associated protein 1
IDBP-713659
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137221:
This gene encodes a tight junction-associated protein. Incorporation of the encoded protein into tight junctions occurs at a late stage of formation of the junctions. The encoded protein localizes to the Golgi and may function in vesicle trafficking. Alternatively spliced transcript variants have been described. A related pseudogene exists on the X chromosome. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:46257851-46283026
Strand Reverse strand
Band C
Transcripts
ENSMUST00000012440 ENSMUSP00000012440
ENSMUST00000164342 ENSMUSP00000130710
ENSMUST00000180283 ENSMUSP00000137220
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007030 Golgi organization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0005923 tight junction
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000137221
View Gene Order
ENSBTAG00000011189
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04530
Tight junction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
hsa04530
Tight junction pathway
INOH
PID NCI
Cross-References
SwissProt Q9DCD5
TrEMBL I7H459
UniProt Splice Variant
Entrez Gene 74094
UniGene Mm.284594 Mm.490566
RefSeq NM_001252475 NM_001252473 NM_001252474 NM_028751
OMIM
CCDS CCDS28824
HPRD
IMGT
MGI ID MGI:1921344
MGI Symbol Tjap1
EMBL AB712252 AF465982 AK002882 AK169889 BC023316
GenPept AAH23316 AAL76253 BAB22429 BAE41438 BAM29296
RNA Seq Atlas 74094

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca