Version 5.4
Homo sapiens Gene: TJAP1
Summary
InnateDB Gene IDBG-88201.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TJAP1
Gene Name tight junction associated protein 1 (peripheral)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000137221
Encoded Proteins
IDBP-88203
tight junction associated protein 1 (peripheral)
IDBP-88205
tight junction associated protein 1 (peripheral)
IDBP-88209
tight junction associated protein 1 (peripheral)
IDBP-88211
tight junction associated protein 1 (peripheral)
IDBP-88213
tight junction associated protein 1 (peripheral)
IDBP-88215
tight junction associated protein 1 (peripheral)
IDBP-379656
tight junction associated protein 1 (peripheral)
IDBP-379657
tight junction associated protein 1 (peripheral)
IDBP-379658
tight junction associated protein 1 (peripheral)
IDBP-379660
tight junction associated protein 1 (peripheral)
IDBP-813563
tight junction associated protein 1 (peripheral)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a tight junction-associated protein. Incorporation of the encoded protein into tight junctions occurs at a late stage of formation of the junctions. The encoded protein localizes to the Golgi and may function in vesicle trafficking. Alternatively spliced transcript variants have been described. A related pseudogene exists on the X chromosome. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:43477523-43506556
Strand Forward strand
Band p21.1
Transcripts
ENST00000372454 ENSP00000361532
ENST00000259751 ENSP00000259751
ENST00000372449 ENSP00000361527
ENST00000372452 ENSP00000361530
ENST00000372445 ENSP00000361522
ENST00000372444 ENSP00000361521
ENST00000436109 ENSP00000407080
ENST00000442878 ENSP00000390981
ENST00000438588 ENSP00000408769
ENST00000454762 ENSP00000391115
ENST00000483640
ENST00000478173
ENST00000459851
ENST00000490050
ENST00000612912 ENSP00000484142
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007030 Golgi organization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0005923 tight junction
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000012296
View Gene Order
ENSBTAG00000011189
Not yet available
Pathways
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
hsa04530
Tight junction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001146016 NM_001146017 NM_001146018 NM_001146019 NM_001146020 NM_080604 XM_006715249 XM_006715250 XM_006715254 XM_006715256 XM_006715258 XM_006715259 XM_006715260 XM_006715261 XM_006715263 XM_006715264 XM_006715265 XM_006715266 XM_006715271
HUGO
OMIM
CCDS CCDS4898 CCDS55004
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca