Version 5.4
Mus musculus Gene: Plxnc1
Summary
InnateDB Gene IDBG-186904.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plxnc1
Gene Name plexin C1
Synonyms 2510048K12Rik; AW742158; CD232; Vespr
Species Mus musculus
Ensembl Gene ENSMUSG00000074785
Encoded Proteins
IDBP-186906
plexin C1
IDBP-713679
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136040:
This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:94790866-94944578
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000099337 ENSMUSP00000096939
ENSMUST00000180514
ENSMUST00000181244 ENSMUSP00000138038
ENSMUST00000180573
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007275 multicellular organismal development
Cellular Component
GO:0005622 intracellular
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000136040
View Gene Order
ENSBTAG00000011245
Not yet available
Pathways
NETPATH
REACTOME
REACT_261444
Axon guidance pathway
REACT_188576
Developmental Biology pathway
REACT_263034
Semaphorin interactions pathway
REACT_231928
Other semaphorin interactions pathway
KEGG
mmu04360
Axon guidance pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19200
Other semaphorin interactions pathway
REACT_111045
Developmental Biology pathway
REACT_19271
Semaphorin interactions pathway
REACT_18266
Axon guidance pathway
KEGG
hsa04360
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.256712
RefSeq NM_018797
OMIM
CCDS CCDS48676
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca