Version 5.4
Mus musculus Gene: Epha10
Summary
InnateDB Gene IDBG-187075.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Epha10
Gene Name Eph receptor A10
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000028876
Encoded Proteins
IDBP-187077
Eph receptor A10
IDBP-534486
Eph receptor A10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000183317:
Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:124880899-124917800
Strand Forward strand
Band D2.2
Transcripts
ENSMUST00000059343 ENSMUSP00000050810
ENSMUST00000149146 ENSMUSP00000118801
ENSMUST00000151791
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005003 ephrin receptor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0048013 ephrin receptor signaling pathway
Cellular Component
GO:0005887 integral component of plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000183317
View Gene Order
ENSBTAG00000020510
Not yet available
Pathways
NETPATH
REACTOME
REACT_243939
EPHA-mediated growth cone collapse pathway
REACT_243590
EPH-ephrin mediated repulsion of cells pathway
REACT_258158
EPH-Ephrin signaling pathway
REACT_261444
Axon guidance pathway
REACT_188576
Developmental Biology pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
REACT_228063
EPHA-mediated growth cone collapse pathway
REACT_228189
EPH-ephrin mediated repulsion of cells pathway
REACT_228170
EPH-Ephrin signaling pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8BYG9
TrEMBL
UniProt Splice Variant
Entrez Gene 230735
UniGene Mm.171490 Mm.404473 Mm.460330 Mm.462513
RefSeq NM_001256432 NM_177671
OMIM
CCDS CCDS18630
HPRD
IMGT
MGI ID MGI:3586824
MGI Symbol Epha10
EMBL AK039700 AK143168 AL606933 BC116991 BC119084
GenPept AAI16992 AAI19085 BAC30423 BAE25289 CAM16103 CAM16104
RNA Seq Atlas 230735

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca