Version 5.4
Homo sapiens Gene: CHIC2
Summary
InnateDB Gene IDBG-18712.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHIC2
Gene Name cysteine-rich hydrophobic domain 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000109220
Encoded Proteins
IDBP-18716
cysteine-rich hydrophobic domain 2
IDBP-482342
cysteine-rich hydrophobic domain 2
IDBP-479000
cysteine-rich hydrophobic domain 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:54009789-54064690
Strand Reverse strand
Band q12
Transcripts
ENST00000263921 ENSP00000263921
ENST00000512964 ENSP00000425238
ENST00000510894 ENSP00000421032
ENST00000509678
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 11 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005794 Golgi apparatus
GO:0005798 Golgi-associated vesicle
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029229
View Gene Order
ENSBTAG00000032660
Not yet available
Cross-References
SwissProt
TrEMBL D6RDW7
UniProt Splice Variant
Entrez Gene 26511
UniGene Hs.712904
RefSeq NM_012110
HUGO HGNC:1935
OMIM 604332
CCDS CCDS3493
HPRD 10373
IMGT
EMBL AC110792
GenPept
RNA Seq Atlas 26511

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca