Version 5.4
Mus musculus Gene: Mrpl42
Summary
InnateDB Gene IDBG-187147.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mrpl42
Gene Name mitochondrial ribosomal protein L42
Synonyms 2700009F22Rik; 2900055D03Rik; D10Ertd322e; HSPC204; L31mt; MRP-L31; PTD007; Rpml31
Species Mus musculus
Ensembl Gene ENSMUSG00000062981
Encoded Proteins
IDBP-187149
mitochondrial ribosomal protein L42
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198015:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:95480806-95501927
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000075829 ENSMUSP00000075226
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0044822 poly(A) RNA binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198015
View Gene Order
ENSBTAG00000002708
Not yet available
Pathways
NETPATH
REACTOME
REACT_268789
Mitochondrial translation pathway
REACT_224594
Organelle biogenesis and maintenance pathway
REACT_270125
Mitochondrial translation elongation pathway
REACT_271096
Mitochondrial translation initiation pathway
REACT_270158
Mitochondrial translation termination pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_200751
Organelle biogenesis and maintenance pathway
REACT_267673
Mitochondrial translation pathway
REACT_267680
Mitochondrial translation initiation pathway
REACT_267602
Mitochondrial translation termination pathway
REACT_267677
Mitochondrial translation elongation pathway
REACT_270797
Mitochondrial translation initiation pathway
REACT_271447
Mitochondrial translation elongation pathway
REACT_270450
Mitochondrial translation pathway
REACT_270960
Mitochondrial translation termination pathway
REACT_219259
Organelle biogenesis and maintenance pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9CPV3
TrEMBL
UniProt Splice Variant
Entrez Gene 67270
UniGene
RefSeq NM_026065 XM_006513979
OMIM
CCDS CCDS24137
HPRD
IMGT
MGI ID MGI:1333774
MGI Symbol Mrpl42
EMBL AK002530 AK003427 AK013693 BC024337
GenPept AAH24337 BAB22166 BAB22785 BAB28957
RNA Seq Atlas 67270

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca