Homo sapiens Gene: MUC6
Summary
InnateDB Gene IDBG-18722.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MUC6
Gene Name mucin 6, oligomeric mucus/gel-forming
Synonyms MUC-6
Species Homo sapiens
Ensembl Gene ENSG00000184956
Encoded Proteins
mucin 6, oligomeric mucus/gel-forming
mucin 6, oligomeric mucus/gel-forming
mucin 6, oligomeric mucus/gel-forming
mucin 6, oligomeric mucus/gel-forming
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract (summary by Toribara et al., 1993 [PubMed 7680650]).[supplied by OMIM, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:1012821-1036706
Strand Reverse strand
Band p15.5
Transcripts
ENST00000421673 ENSP00000406861
ENST00000532016 ENSP00000433246
ENST00000527242 ENSP00000436903
ENST00000525923 ENSP00000433790
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005201 extracellular matrix structural constituent
Biological Process
GO:0016266 O-glycan processing
GO:0030277 maintenance of gastrointestinal epithelium
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005796 Golgi lumen
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Termination of O-glycan biosynthesis pathway
O-linked glycosylation of mucins pathway
Post-translational protein modification pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 4588
UniGene Hs.528432 Hs.703727
RefSeq NM_005961
HUGO HGNC:7517
OMIM 158374
CCDS CCDS44513
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 4588