Version 5.4
Mus musculus Gene: Elmo3
Summary
InnateDB Gene IDBG-187241.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Elmo3
Gene Name engulfment and cell motility 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000014791
Encoded Proteins
IDBP-262521
engulfment and cell motility 3, ced-12 homolog (C. elegans)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102890:
The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:105305601-105310623
Strand Forward strand
Band D3
Transcripts
ENSMUST00000109375 ENSMUSP00000105000
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0017124 SH3 domain binding
Biological Process
GO:0006909 phagocytosis
GO:0006915 apoptotic process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000102890
View Gene Order
ENSBTAG00000001286
Not yet available
Cross-References
SwissProt Q8BYZ7
TrEMBL
UniProt Splice Variant
Entrez Gene 234683
UniGene Mm.237966
RefSeq NM_172760
OMIM
CCDS CCDS22598
HPRD
IMGT
MGI ID MGI:2679007
MGI Symbol Elmo3
EMBL AK037067 BC058752 BC138887 CH466525
GenPept AAH58752 AAI38888 BAC29692 EDL11267
RNA Seq Atlas 234683

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca