Version 5.4
Homo sapiens Gene: ELMO3
Summary
InnateDB Gene IDBG-36322.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELMO3
Gene Name engulfment and cell motility 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000102890
Encoded Proteins
IDBP-36324
engulfment and cell motility 3
IDBP-242483
engulfment and cell motility 3
IDBP-753810
IDBP-751558
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:67199111-67204029
Strand Forward strand
Band q22.1
Transcripts
ENST00000360833 ENSP00000354077
ENST00000393997 ENSP00000377566
ENST00000477898 ENSP00000458539
ENST00000571587 ENSP00000461166
ENST00000571638
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0017124 SH3 domain binding
Biological Process
GO:0006909 phagocytosis
GO:0006915 apoptotic process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000014791
View Gene Order
ENSBTAG00000001286
Not yet available
Cross-References
SwissProt Q96BJ8
TrEMBL
UniProt Splice Variant
Entrez Gene 79767
UniGene Hs.377416
RefSeq NM_024712
HUGO HGNC:17289
OMIM 606422
CCDS CCDS10833
HPRD 12104
IMGT
EMBL AC040160 AK023886 AK300976 BC015524 BC034410
GenPept AAH15524 AAH34410 BAB14712 BAG62598
RNA Seq Atlas 79767

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca