Version 5.4
Mus musculus Gene: Btg1
Summary
InnateDB Gene IDBG-187437.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Btg1
Gene Name B cell translocation gene 1, anti-proliferative
Synonyms AI426953; AW546738
Species Mus musculus
Ensembl Gene ENSMUSG00000036478
Encoded Proteins
IDBP-187439
B-cell translocation gene 1, anti-proliferative
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000133639:
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:96617001-96622813
Strand Forward strand
Band C3
Transcripts
ENSMUST00000038377 ENSMUSP00000038863
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019899 enzyme binding
Biological Process
GO:0006479 protein methylation
GO:0006979 response to oxidative stress
GO:0007283 spermatogenesis
GO:0008285 negative regulation of cell proliferation
GO:0043085 positive regulation of catalytic activity
GO:0043434 response to peptide hormone
GO:0045603 positive regulation of endothelial cell differentiation
GO:0045663 positive regulation of myoblast differentiation
GO:0045766 positive regulation of angiogenesis
GO:2000271 positive regulation of fibroblast apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000133639
View Gene Order
ENSBTAG00000020330
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03018
RNA degradation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03018
RNA degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.23811 Mm.396231 Mm.408347 Mm.427971
RefSeq NM_007569
OMIM
CCDS CCDS24140
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca