Homo sapiens Gene: STAP2
Summary
InnateDB Gene IDBG-18753.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STAP2
Gene Name signal transducing adaptor family member 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000178078
Encoded Proteins
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
STAP2 acts as an endogenous negative regulator of EBV LMP1-mediated signalling through TRAF3 and TRADD.
Entrez Gene
Summary This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:4324043-4342786
Strand Reverse strand
Band p13.3
Transcripts
ENST00000598443 ENSP00000471281
ENST00000601179
ENST00000594605 ENSP00000471052
ENST00000601482 ENSP00000472851
ENST00000597593
ENST00000600324 ENSP00000468927
ENST00000596242
ENST00000601956 ENSP00000469657
ENST00000599736 ENSP00000470321
ENST00000602007
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated
Total 20 [view]
Protein-Protein 19 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.194385 Hs.739845
RefSeq NM_001013841 NM_017720 XM_005259592 XM_006722790 XM_006722791
HUGO
OMIM
CCDS CCDS12128 CCDS45926
HPRD 07430
IMGT
EMBL
GenPept
RNA Seq Atlas