Version 5.4
Bos taurus Gene: STAP2
Summary
InnateDB Gene IDBG-644280.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STAP2
Gene Name signal-transducing adaptor protein 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006001
Encoded Proteins
IDBP-696914
signal-transducing adaptor protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 18573890
[Homo sapiens] STAP2 acts as an endogenous negative regulator of EBV LMP1-mediated signalling through TRAF3 and TRADD.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178078:
This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:20966851-20978542
Strand Forward strand
Band
Transcripts
ENSBTAT00000007881 ENSBTAP00000007881
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000178078
View Gene Order
ENSMUSG00000038781
View Gene Order
Cross-References
SwissProt
TrEMBL Q3ZCE1
UniProt Splice Variant
Entrez Gene 505456
UniGene Bt.49538
RefSeq NM_001034246
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102497 DAAA02019610 DAAA02019611
GenPept AAI02498
RNA Seq Atlas 505456

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca