Version 5.4
Mus musculus Gene: Tenc1
Summary
InnateDB Gene IDBG-187550.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tenc1
Gene Name tensin like C1 domain-containing phosphatase
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000037003
Encoded Proteins
IDBP-187554
tensin like C1 domain-containing phosphatase
IDBP-625684
tensin like C1 domain-containing phosphatase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111077:
The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:102102988-102116401
Strand Forward strand
Band F2
Transcripts
ENSMUST00000046144 ENSMUSP00000041087
ENSMUST00000169627 ENSMUSP00000129146
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004721 phosphoprotein phosphatase activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001822 kidney development
GO:0008285 negative regulation of cell proliferation
GO:0014850 response to muscle activity
GO:0016311 dephosphorylation
GO:0019725 cellular homeostasis
GO:0032963 collagen metabolic process
GO:0035264 multicellular organism growth
GO:0035556 intracellular signal transduction
GO:0048871 multicellular organismal homeostasis
Cellular Component
GO:0005886 plasma membrane
GO:0005925 focal adhesion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000111077
View Gene Order
ENSBTAG00000006904
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8CGB6
TrEMBL
UniProt Splice Variant
Entrez Gene 209039
UniGene Mm.29389
RefSeq XM_006520688 XM_006520690 XM_006520691 XM_006520693 NM_153533 XM_006520689 XM_006520692 XM_006520694
OMIM
CCDS CCDS37224
HPRD
IMGT
MGI ID MGI:2387586
MGI Symbol Tenc1
EMBL AF424789 AK147789 AK158009 BC025818 BC042190
GenPept AAH25818 AAH42190 AAN32753 BAE28139 BAE34316
RNA Seq Atlas 209039

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca