Mus musculus Gene: Atp2b1 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-187658.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Atp2b1 | ||||||||||||||||||||||
Gene Name | ATPase, Ca++ transporting, plasma membrane 1 | ||||||||||||||||||||||
Synonyms | 2810442I22Rik; E130111D10Rik; Pmca1 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000019943 | ||||||||||||||||||||||
Encoded Proteins |
ATPase, Ca++ transporting, plasma membrane 1
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000070961:
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 10:98915152-99026143 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | C3 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME | |||||||||||||||||||||||
KEGG |
Calcium signaling pathway pathway
Salivary secretion pathway
Pancreatic secretion pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Reduction of cytosolic Ca++ levels pathway
Platelet homeostasis pathway
Ion transport by P-type ATPases pathway
Transmembrane transport of small molecules pathway
Platelet calcium homeostasis pathway
Ion channel transport pathway
Hemostasis pathway
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KEGG |
Calcium signaling pathway pathway
Pancreatic secretion pathway
Salivary secretion pathway
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INOH | |||||||||||||||||||||||
PID NCI |
C-MYB transcription factor network
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | G5E829 Q3TC38 Q3TDJ2 Q3TSK3 Q6PG79 Q8K314 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 67972 | ||||||||||||||||||||||
UniGene | Mm.166944 Mm.409498 Mm.472543 | ||||||||||||||||||||||
RefSeq | NM_026482 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS24145 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:104653 | ||||||||||||||||||||||
MGI Symbol | Atp2b1 | ||||||||||||||||||||||
EMBL | AC153906 AC160410 AK161995 AK170163 AK170926 BC029045 BC049262 BC057180 CH466539 | ||||||||||||||||||||||
GenPept | AAH29045 AAH49262 AAH57180 BAE36672 BAE41609 BAE42119 EDL21639 | ||||||||||||||||||||||
RNA Seq Atlas | 67972 | ||||||||||||||||||||||