Version 5.4
Mus musculus Gene: Eno2
Summary
InnateDB Gene IDBG-187789.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eno2
Gene Name enolase 2, gamma neuronal
Synonyms AI837106; D6Ertd375e; Eno-2; NSE
Species Mus musculus
Ensembl Gene ENSMUSG00000004267
Encoded Proteins
IDBP-187793
enolase 2, gamma neuronal
IDBP-255926
enolase 2, gamma neuronal
IDBP-540962
enolase 2, gamma neuronal
IDBP-532680
enolase 2, gamma neuronal
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111674:
This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:124760053-124769673
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000004378 ENSMUSP00000004378
ENSMUST00000112476 ENSMUSP00000108095
ENSMUST00000147307
ENSMUST00000125436
ENSMUST00000139763
ENSMUST00000146712
ENSMUST00000128598
ENSMUST00000138770
ENSMUST00000135626 ENSMUSP00000114500
ENSMUST00000151214
ENSMUST00000127274
ENSMUST00000149652 ENSMUSP00000119112
ENSMUST00000128701
ENSMUST00000147004
ENSMUST00000156033
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 34 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004634 phosphopyruvate hydratase activity
Biological Process
GO:0006096 glycolytic process
Cellular Component
GO:0000015 phosphopyruvate hydratase complex
GO:0001917 photoreceptor inner segment
GO:0005615 extracellular space
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0043025 neuronal cell body
GO:0043204 perikaryon
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000111674
View Gene Order
ENSBTAG00000011274
Not yet available
Pathways
NETPATH
REACTOME
REACT_189085
Disease pathway
REACT_232322
Glycolysis pathway
REACT_261601
Glucose metabolism pathway
REACT_188937
Metabolism pathway
REACT_263230
Gluconeogenesis pathway
REACT_203949
Glycogen storage diseases pathway
REACT_203841
Myoclonic epilepsy of Lafora pathway
REACT_248571
Metabolism of carbohydrates pathway
KEGG
mmu00010
Glycolysis / Gluconeogenesis pathway
mmu03018
RNA degradation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_11
TCR pathway
REACTOME
REACT_1383
Glycolysis pathway
REACT_1520
Gluconeogenesis pathway
REACT_200783
Myoclonic epilepsy of Lafora pathway
REACT_474
Metabolism of carbohydrates pathway
REACT_111217
Metabolism pathway
REACT_116125
Disease pathway
REACT_723
Glucose metabolism pathway
REACT_200833
Glycogen storage diseases pathway
KEGG
hsa00010
Glycolysis / Gluconeogenesis pathway
hsa03018
RNA degradation pathway
INOH
INOH website
Citrate cycle pathway
INOH website
Glycolysis Gluconeogenesis pathway
PID NCI
Cross-References
SwissProt
TrEMBL D3Z2S4
UniProt Splice Variant
Entrez Gene 13807
UniGene Mm.3913 Mm.396813 Mm.488778
RefSeq NM_013509 XM_006505503 XM_006505504 XM_006505505
OMIM
CCDS CCDS20527
HPRD
IMGT
MGI ID MGI:95394
MGI Symbol Eno2
EMBL AC164157
GenPept
RNA Seq Atlas 13807

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca