InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Atp5k

Summary

InnateDB Gene

IDBG-188029.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp5k

Gene Name

ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e

Synonyms

2610008D24Rik; Atp5i; Lfm1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000050856

Encoded Proteins

IDBP-188031

ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e

IDBP-400438

ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169020:
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the e subunit of the Fo complex. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:108433244-108434448

Strand

Reverse strand

Band

Transcripts

ENSMUST00000049628	ENSMUSP00000051222
ENSMUST00000118632	ENSMUSP00000113882
ENSMUST00000123184

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015078	hydrogen ion transmembrane transporter activity
GO:0016887	ATPase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0015986	ATP synthesis coupled proton transport
GO:0046034	ATP metabolic process

Cellular Component

GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
GO:0005739	mitochondrion
GO:0005753	mitochondrial proton-transporting ATP synthase complex