Version 5.4
| Mus musculus Gene: Glp2r | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-188182.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Glp2r | ||||||||
| Gene Name | glucagon-like peptide 2 receptor | ||||||||
| Synonyms | 9530092J08Rik; GLP-2 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000049928 | ||||||||
| Encoded Proteins |
glucagon-like peptide 2 receptor
glucagon-like peptide 2 receptor
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000065325:
The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 11:67661502-67771153 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | B3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
G alpha (s) signalling events pathway
Glucagon-type ligand receptors pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class B/2 (Secretin family receptors) pathway
GPCR ligand binding pathway
Signal Transduction pathway
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| KEGG |
Neuroactive ligand-receptor interaction pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
G alpha (s) signalling events pathway
Glucagon-type ligand receptors pathway
Class B/2 (Secretin family receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
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| KEGG |
Neuroactive ligand-receptor interaction pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q5IXF8 | ||||||||
| TrEMBL | Q80UB5 Q8BM22 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 93896 | ||||||||
| UniGene | Mm.118883 Mm.403068 | ||||||||
| RefSeq | NM_175681 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS24860 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:2136733 | ||||||||
| MGI Symbol | Glp2r | ||||||||
| EMBL | AK035702 AL646097 AY255567 AY605231 | ||||||||
| GenPept | AAO85079 AAT46060 BAC29159 CAI25249 | ||||||||
| RNA Seq Atlas | 93896 | ||||||||