Version 5.4
Mus musculus Gene: Atf7
Summary
InnateDB Gene IDBG-189070.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atf7
Gene Name activating transcription factor 7
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000052414
Encoded Proteins
IDBP-263703
activating transcription factor 7
IDBP-626129
activating transcription factor 7
IDBP-788712
predicted gene, 28047
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 26322480
Atf7, a stress-response transcription factor, mediates epigenetic changes in macrophages involved in innate immunological memory in response to lipopolysaccharide.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000267281:
Gene Information
Type Protein coding
Genomic Location Chromosome 15:102523843-102625067
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000108828 ENSMUSP00000104456
ENSMUST00000169033 ENSMUSP00000130130
ENSMUST00000184772 ENSMUSP00000138975
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 4 [view]
Protein-DNA 6 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0045087 innate immune response (InnateDB)
Cellular Component
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000267281
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_146065
OMIM
CCDS CCDS37230
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca