InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Myf6

Summary

InnateDB Gene

IDBG-189164.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Myf6

Gene Name

myogenic factor 6

Synonyms

bHLHc4; herculin; MRF4

Species

Mus musculus

Ensembl Gene

ENSMUSG00000035923

Encoded Proteins

IDBP-189166

myogenic factor 6

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111046:
The protein encoded by this gene is a probable basic helix-loop-helix (bHLH) DNA binding protein involved in muscle differentiation. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of autosomal dominant centronuclear myopathy (ADCNM). [provided by RefSeq, May 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:107492860-107494729

Strand

Reverse strand

Band

Transcripts

ENSMUST00000044210

ENSMUSP00000047529

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0046983	protein dimerization activity

Biological Process

GO:0001756	somitogenesis
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0007517	muscle organ development
GO:0007519	skeletal muscle tissue development
GO:0035914	skeletal muscle cell differentiation
GO:0043403	skeletal muscle tissue regeneration
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0060415	muscle tissue morphogenesis