Version 5.4
Mus musculus Gene: Hoxc10
Summary
InnateDB Gene IDBG-189315.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hoxc10
Gene Name homeobox C10
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000022484
Encoded Proteins
IDBP-189317
homeobox C10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000180818:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:102966796-102971893
Strand Forward strand
Band F3
Transcripts
ENSMUST00000001699 ENSMUSP00000001699
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001501 skeletal system development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0009952 anterior/posterior pattern specification
GO:0009954 proximal/distal pattern formation
GO:0021520 spinal cord motor neuron cell fate specification
GO:0030326 embryonic limb morphogenesis
GO:0050905 neuromuscular process
Cellular Component
GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000180818
View Gene Order
ENSBTAG00000003278
Not yet available
Cross-References
SwissProt P31257
TrEMBL Q8BZY5
UniProt Splice Variant
Entrez Gene 209448
UniGene Mm.31665
RefSeq NM_010462
OMIM
CCDS CCDS57014
HPRD
IMGT
MGI ID MGI:96192
MGI Symbol Hoxc10
EMBL AK033186 BC053405 M81658 X63507
GenPept AAA63310 AAH53405 BAC28189
RNA Seq Atlas 209448

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca