Version 5.4
Mus musculus Gene: Tapbpl
Summary
InnateDB Gene IDBG-189696.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tapbpl
Gene Name TAP binding protein-like
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038213
Encoded Proteins
IDBP-189698
TAP binding protein-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139192:
Tapasin, or TAPBP (MIM 601962), is a member of the variable-constant Ig superfamily that links major histocompatibility complex (MHC) class I molecules to the transporter associated with antigen processing (TAP; see MIM 170260) in the endoplasmic reticulum (ER). The TAPBP gene is located near the MHC complex on chromosome 6p21.3. TAPBPL is a member of the Ig superfamily that is localized on chromosome 12p13.3, a region somewhat paralogous to the MHC.[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:125223933-125231860
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000043422 ENSMUSP00000047105
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0032403 protein complex binding
Biological Process
GO:0002590 negative regulation of antigen processing and presentation of peptide antigen via MHC class I
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000139192
View Gene Order
ENSBTAG00000014728
Not yet available
Cross-References
SwissProt Q8VD31
TrEMBL
UniProt Splice Variant
Entrez Gene 213233
UniGene Mm.296902
RefSeq NM_145391 XM_006505862
OMIM
CCDS CCDS20547
HPRD
IMGT
MGI ID MGI:2384853
MGI Symbol Tapbpl
EMBL AC140324 BC017613
GenPept AAH17613
RNA Seq Atlas 213233

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca