Version 5.4
Mus musculus Gene: Mthfs
Summary
InnateDB Gene IDBG-190400.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mthfs
Gene Name 5, 10-methenyltetrahydrofolate synthetase
Synonyms 1110034I12Rik; 2310020H23Rik; AI119695
Species Mus musculus
Ensembl Gene ENSMUSG00000066442
Encoded Proteins
IDBP-190402
5, 10-methenyltetrahydrofolate synthetase
IDBP-400514
5, 10-methenyltetrahydrofolate synthetase
IDBP-536873
5, 10-methenyltetrahydrofolate synthetase
IDBP-790052
5, 10-methenyltetrahydrofolate synthetase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 9:89210676-89377713
Strand Forward strand
Band E3.1
Transcripts
ENSMUST00000085256 ENSMUSP00000082354
ENSMUST00000118870 ENSMUSP00000112695
ENSMUST00000117314
ENSMUST00000118887
ENSMUST00000138109 ENSMUSP00000119881
ENSMUST00000127438
ENSMUST00000144930
ENSMUST00000149688
ENSMUST00000127868
ENSMUST00000147644
ENSMUST00000186009
ENSMUST00000187362
ENSMUST00000185894 ENSMUSP00000139738
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0005542 folic acid binding
GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity
Biological Process
GO:0009396 folic acid-containing compound biosynthetic process
GO:0046653 tetrahydrofolate metabolic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu00670
One carbon pool by folate pathway
INOH
PID NCI
Cross-References
SwissProt Q9D110
TrEMBL D3YTV6 D3Z0T4
UniProt Splice Variant
Entrez Gene 107885
UniGene Mm.461300 Mm.486274
RefSeq NM_026829
OMIM
CCDS CCDS23394
HPRD
IMGT
MGI ID MGI:1340032
MGI Symbol Mthfs
EMBL AC135634 AK004092 CT030686
GenPept BAB23165 CAQ52322
RNA Seq Atlas 107885

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca