Version 5.4
Mus musculus Gene: Zic1
Summary
InnateDB Gene IDBG-190975.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zic1
Gene Name zinc finger protein of the cerebellum 1
Synonyms ZIC; ZNF201
Species Mus musculus
Ensembl Gene ENSMUSG00000032368
Encoded Proteins
IDBP-190977
zinc finger protein of the cerebellum 1
IDBP-190979
zinc finger protein of the cerebellum 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152977:
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:91358058-91365810
Strand Reverse strand
Band E3.2
Transcripts
ENSMUST00000034927 ENSMUSP00000034927
ENSMUST00000065360 ENSMUSP00000068858
ENSMUST00000173121
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001501 skeletal system development
GO:0006351 transcription, DNA-templated
GO:0007389 pattern specification process
GO:0007417 central nervous system development
GO:0007420 brain development
GO:0007628 adult walking behavior
GO:0008589 regulation of smoothened signaling pathway
GO:0021510 spinal cord development
GO:0030154 cell differentiation
GO:0042307 positive regulation of protein import into nucleus
GO:0042472 inner ear morphogenesis
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000152977
View Gene Order
ENSBTAG00000014751
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.335350 Mm.443627 Mm.477226
RefSeq NM_009573 XM_006511061
OMIM
CCDS CCDS23403
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca