Version 5.4
Mus musculus Gene: Pacsin3
Summary
InnateDB Gene IDBG-190993.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pacsin3
Gene Name protein kinase C and casein kinase substrate in neurons 3
Synonyms 4921507A02Rik; 6330413E15Rik; AW413130
Species Mus musculus
Ensembl Gene ENSMUSG00000027257
Encoded Proteins
IDBP-190995
protein kinase C and casein kinase substrate in neurons 3
IDBP-190997
protein kinase C and casein kinase substrate in neurons 3
IDBP-258323
protein kinase C and casein kinase substrate in neurons 3
IDBP-535022
protein kinase C and casein kinase substrate in neurons 3
IDBP-534283
protein kinase C and casein kinase substrate in neurons 3
IDBP-535124
protein kinase C and casein kinase substrate in neurons 3
IDBP-537837
protein kinase C and casein kinase substrate in neurons 3
IDBP-533435
protein kinase C and casein kinase substrate in neurons 3
IDBP-539367
protein kinase C and casein kinase substrate in neurons 3
IDBP-538309
protein kinase C and casein kinase substrate in neurons 3
IDBP-624848
protein kinase C and casein kinase substrate in neurons 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165912:
This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:91255954-91264679
Strand Forward strand
Band E1
Transcripts
ENSMUST00000059566 ENSMUSP00000054391
ENSMUST00000028694 ENSMUSP00000028694
ENSMUST00000111349 ENSMUSP00000106981
ENSMUST00000134699 ENSMUSP00000115046
ENSMUST00000143883
ENSMUST00000154959 ENSMUSP00000122769
ENSMUST00000144394 ENSMUSP00000121297
ENSMUST00000156919 ENSMUSP00000122779
ENSMUST00000131711 ENSMUSP00000117214
ENSMUST00000124658
ENSMUST00000138470 ENSMUSP00000117230
ENSMUST00000126754
ENSMUST00000141313
ENSMUST00000128684 ENSMUSP00000118915
ENSMUST00000168916 ENSMUSP00000129175
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 32 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008092 cytoskeletal protein binding
GO:0008289 lipid binding
GO:0019855 calcium channel inhibitor activity
Biological Process
GO:0006897 endocytosis
GO:0045806 negative regulation of endocytosis
GO:0051044 positive regulation of membrane protein ectodomain proteolysis
GO:0051926 negative regulation of calcium ion transport
GO:0097320 membrane tubulation
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000165912
View Gene Order
ENSBTAG00000009576
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.236650
RefSeq NM_001289677 NM_001289678 NM_028733 NM_030880 XM_006500423 XM_006500424 XM_006500425 XM_006500426 XM_006500427 XM_006500428
OMIM
CCDS CCDS16429
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca