Version 5.4
Mus musculus Gene: Klrb1c
Summary
InnateDB Gene IDBG-191576.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klrb1c
Gene Name killer cell lectin-like receptor subfamily B member 1C
Synonyms AI462337; CD161; ly-55c; Ly-59; Ly55c; Ly59; Nk-1; Nk-1.2; NK-RP1; Nk1; NK1.1; Nk1.2; NKR-P1.9; NKRP1; NKRP140; Nkrp1c
Species Mus musculus
Ensembl Gene ENSMUSG00000030325
Encoded Proteins
IDBP-627149
killer cell lectin-like receptor subfamily B member 1C
IDBP-627151
killer cell lectin-like receptor subfamily B member 1C
IDBP-627153
killer cell lectin-like receptor subfamily B member 1C
IDBP-627154
killer cell lectin-like receptor subfamily B member 1C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:128778485-128789215
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000167691 ENSMUSP00000127297
ENSMUST00000174404 ENSMUSP00000134504
ENSMUST00000172601 ENSMUSP00000134184
ENSMUST00000174865 ENSMUSP00000134055
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0030246 carbohydrate binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0030101 natural killer cell activation
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0009897 external side of plasma membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu04650
Natural killer cell mediated cytotoxicity pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9Q3U6 Q7TQ26
UniProt Splice Variant
Entrez Gene 17059
UniGene Mm.480764
RefSeq NM_008527 NM_001159904
OMIM
CCDS CCDS39654 CCDS51919
HPRD
IMGT
MGI ID MGI:107538
MGI Symbol Klrb1c
EMBL AC102693 AY316227
GenPept AAP82935
RNA Seq Atlas 17059

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca