Version 5.4
Mus musculus Gene: Bai2
Summary
InnateDB Gene IDBG-191749.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bai2
Gene Name brain-specific angiogenesis inhibitor 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000028782
Encoded Proteins
IDBP-191751
brain-specific angiogenesis inhibitor 2
IDBP-191753
brain-specific angiogenesis inhibitor 2
IDBP-269627
brain-specific angiogenesis inhibitor 2
IDBP-269629
brain-specific angiogenesis inhibitor 2
IDBP-269631
brain-specific angiogenesis inhibitor 2
IDBP-400192
brain-specific angiogenesis inhibitor 2
IDBP-400196
brain-specific angiogenesis inhibitor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000121753:
BAI1, a p53-target gene, encodes brain-specific angiogenesis inhibitor, a seven-span transmembrane protein and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008]
This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:129984870-130022633
Strand Forward strand
Band D2.2
Transcripts
ENSMUST00000030571 ENSMUSP00000030571
ENSMUST00000097868 ENSMUSP00000095480
ENSMUST00000106018 ENSMUSP00000101639
ENSMUST00000106017 ENSMUSP00000101638
ENSMUST00000106015 ENSMUSP00000101636
ENSMUST00000106012
ENSMUST00000120204 ENSMUSP00000112524
ENSMUST00000121049 ENSMUSP00000112869
ENSMUST00000149282
ENSMUST00000136416
ENSMUST00000136787
ENSMUST00000166118
ENSMUST00000163625
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0005515 protein binding
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007422 peripheral nervous system development
GO:0016525 negative regulation of angiogenesis
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000121753
View Gene Order
ENSBTAG00000010657
Not yet available
Cross-References
SwissProt Q8CGM1
TrEMBL Q80T36 Q80T61
UniProt Splice Variant
Entrez Gene 230775
UniGene Mm.262241
RefSeq NM_001199696 XM_006503053 XM_006536975 NM_001290714 NM_001290715 NM_173071 XM_006503048 XM_006503049 XM_006503050 XM_006503051 XM_006503052 XM_006503055 XM_006503056 XM_006503058 XM_006536970 XM_006536971 XM_006536972 XM_006536973 XM_006536974 XM_006536977 XM_006536980
OMIM
CCDS CCDS57300 CCDS51309 CCDS71478
HPRD
IMGT
MGI ID MGI:2451244
MGI Symbol Bai2
EMBL AK144268 AK144559 AK158735 AL626774 AY168407 AY255577 AY255613 BC056926
GenPept AAH56926 AAN86965 AAO85089 AAO85125 BAE25805 BAE25937 BAE34635 CAM17272 CAM17273 CAQ52064
RNA Seq Atlas 230775

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca