Version 5.4
Mus musculus Gene: Sart3
Summary
InnateDB Gene IDBG-191800.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sart3
Gene Name squamous cell carcinoma antigen recognized by T cells 3
Synonyms AU045857; mKIAA0156
Species Mus musculus
Ensembl Gene ENSMUSG00000018974
Encoded Proteins
IDBP-191802
squamous cell carcinoma antigen recognized by T-cells 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000075856:
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:113742446-113771649
Strand Reverse strand
Band F
Transcripts
ENSMUST00000019118 ENSMUSP00000019118
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.
Predicted by orthology
Total 43 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000902 cell morphogenesis
GO:0006396 RNA processing
GO:0010468 regulation of gene expression
GO:0048872 homeostasis of number of cells
GO:0071425 hematopoietic stem cell proliferation
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016607 nuclear speck
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000075856
View Gene Order
ENSBTAG00000031846
Not yet available
Cross-References
SwissProt Q9JLI8
TrEMBL
UniProt Splice Variant
Entrez Gene 53890
UniGene
RefSeq NM_016926
OMIM
CCDS CCDS19552
HPRD
IMGT
MGI ID MGI:1858230
MGI Symbol Sart3
EMBL AF172722 AK053828 AK086398 AK129067 BC036350 BC057156
GenPept AAF65228 AAH36350 AAH57156 BAC35544 BAC39661 BAC97877
RNA Seq Atlas 53890

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca