Homo sapiens Gene: SART3 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-55333.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | SART3 | ||||||||||||||||||
Gene Name | squamous cell carcinoma antigen recognized by T cells 3 | ||||||||||||||||||
Synonyms | DSAP1; P100; p110; p110(nrb); RP11-13G14; TIP110 | ||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000075856 | ||||||||||||||||||
Encoded Proteins |
squamous cell carcinoma antigen recognized by T cells 3
squamous cell carcinoma antigen recognized by T cells 3
squamous cell carcinoma antigen recognized by T cells 3
squamous cell carcinoma antigen recognized by T cells 3
squamous cell carcinoma antigen recognized by T cells 3
squamous cell carcinoma antigen recognized by T cells 3
squamous cell carcinoma antigen recognized by T cells 3
squamous cell carcinoma antigen recognized by T cells 3
squamous cell carcinoma antigen recognized by T cells 3
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 12:108522580-108561400 | ||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||
Band | q23.3 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 93 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | |||||||||||||||||||
UniGene | |||||||||||||||||||
RefSeq | NM_014706 | ||||||||||||||||||
HUGO | |||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS9117 | ||||||||||||||||||
HPRD | 11532 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | |||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||